Alagille Syndrome Market, Revenue Share Analysis, Region & Country Forecast, 2021–2028
According to the most recent analysis by Emergen Research,
the global Alagille
Syndrome market had a value of USD 361.89 million in 2021 and is
anticipated to grow at a rate of 5.8% during the projected period. The
introduction of novel and enhanced diagnostic platforms for early diagnosis,
rising prevalence of alagille syndrome, and rising number of clinical studies
and trials in the area of alagille syndrome-based treatments are key factors
propelling market revenue growth.
A uncommon hereditary condition known as Alagille syndrome
mostly affects the liver. The consequences subsequently spread to the body's
other organs. Because there are fewer tiny bile ducts present inside the liver
in alagille syndrome, bile builds up. This may then result in liver damage and
scarring.
Restraints
One of the key factors driving the market's expansion is the
rising incidence of cancer on a global scale. Other factors supporting the market's
expansion include increasing spending on the construction of healthcare
infrastructure and a rise in demand for novel cures and treatments. Others
indirect factors that would generate attractive market growth prospects include
increased paraganglioma incidences, increasing personal disposable income, and
strategic collaboration and licencing agreements among the leading companies
for the development of treatments.
The lack of knowledge
caused by the rarity of the diseases and the unfavourable reimbursement
situation in developing and underdeveloped nations, however, would be a
significant obstacle to the market's expansion. The market growth rate would be
further hampered by a high number of product recalls.
The underdeveloped economies' lack of knowledge and medical
experience, as well as the restricted operating revenue potential for research
and development professionals, will further impede market expansion.
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Some Key Highlights From the Report
In 2021, the genetic testing market contributed a sizeable
portion of total revenue. Alagille syndrome (ALGS), which is caused by genetic
abnormalities in the Jagged 1 (JAG1), Notch 2 (NOTCH2), or 20p12 chromosomal
deletion, is best diagnosed by genetic testing. Accurate genetic testing
identifies over 95% of patients with clinical symptoms and an ALGS-related
mutation.
Using cellular DNA
extraction and analysis, a medical professional performs this process in a lab
setting to look for genetic anomalies that could be the cause of the disease.
By locating gene variants linked to ALGS, genetic testing can aid in predicting
patient outcomes, recurrence risk, and medical therapy.
In 2021, the hospitals market contributed a sizeable portion
of total revenue. Alagille syndrome can be promptly transferred from patients
with minor symptoms to specialist facilities because to the innovative and
enhanced methods being developed by several hospitals to aid in early detection
of the condition.
In order to adequately evaluate and diagnose patients and
enable them to start therapy as soon as possible. All varieties of alagille
syndrome are treated individually by hospital doctors and medical
professionals, who also administer additional supportive medications to treat
the condition's symptoms and complications.
Some major companies
in the global market report include Albireo Pharma, Inc., Bioarray S.L.,
Mirum Pharmaceuticals, Inc., AbbVie Inc., CANbridge Life Sciences Ltd., Teva
Pharmaceutical Industries Ltd., Takeda Pharmaceutical Company Limited., Endo
International plc, Mylan N.V., Novartis AG, Amneal Pharmaceuticals LLC. and
Epic Pharma, LLC.
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Research Methodology + Table of Content + Infographics@
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Emergen Research has segmented the global alagille syndrome
market based on diagnostic method, treatment type, treatment centers, and
region:
- Diagnostic
Method Outlook (Revenue, USD Million; 2019-2030)
- Genetic
Testing
- Liver
Biopsy
- Heart
and Blood Vessel Tests
- X-ray
Imaging
- Abdominal
Ultrasound
- Kidney
Function Tests
- Treatment
Type Outlook (Revenue, USD Million; 2019-2030)
- Drug
Medications
- Ileal
Bile Acid Transporter (IBAT) inhibitors
- Ursodeoxycholic
Acid
- Cholestyramine
- Rifampicin
- Late
Stage Pipeline Drugs
- Others
- Surgery
- Liver
Transplantation
- Kidney
Surgery
- Others
- Treatment
Centers Outlook (Revenue, USD Million; 2019-2030)
- Hospitals
- Diagnostic
Centers
- Others
- Regional
Outlook (Revenue, USD Million; 2019-2030)
- North
America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- UK
- Italy
- Spain
- Benelux
- Rest
of Europe
- Asia
Pacific
- China
- India
- Japan
- South
Korea
- Rest
of APAC
- Latin
America
- Brazil
- Rest
of LATAM
- Middle
East & Africa
- Saudi
Arabia
- UAE
- South
Africa
- Turkey
- Rest
of Middle East & Africa
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